Product ID:GLUTATHIONE, OXIDIZED, FREE ACID, 3542
MSDS Date:03/31/1999
FSC:6505
NIIN:00N092487
Status Code:A
MSDS Number: CJTCP

Emergency Phone: (800)424-9300

Info Phone: 800-854-3417

Cage: 29089

Telephone: 619-450-5558; 800-854-3417

Cage: 29089

(ORAL, RAT) >5 G/KG

CAS: 27025-41-8

RTECS: MD0556500

LD50 LC50 Mixture:SEE INGREDIENT & TOXICOLOGICAL INFO
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:MAY BE HARMFUL BY INGESTION,
INHALATION OR ABSORPTION THROUGH SKIN. MATERIAL MAY CAUSE
IRRITATION TO THE EYES, SKIN, MUCOUS MEMBRANES AND THE UPPER
RESPIRATORY TRACT.
Effects of Overexposure:SEE HEALTH HAZARDS.

First Aid:SKIN: IN CASES OF SKIN CONTACT, WASH IMMED W/COPIOUS AMOUNTS
OF WATER FOR AT LEAST 15 MINUTES. REMOVE CONTAMINATED CLOTHING AND
SHOES AND WASH BEFORE WEARING. CONSULT A MD. EYES: IN CASES OF EYE
CONTA CT, FLUSH IMMED W/COPIOUS AMOUNTS OF WATER FOR AT LEAST 15
MINUTES. ASSURE ADEQUATE FLUSHING BY SEPARATING EYELIDS W/FINGERS.
CONSULT A MD. INHAL: IN CASES OF INHALATION, REMOVE TO FRESH AIR
AND MONIT OR BREATHING. IF BREATHING BECOMES DIFFICULT, GIVE OXYGEN
AND CONSULT A MD. IF BREATHING STOPS, GIVE ARTIFICIAL RESPIRATION
AND CONSULT A MD. INGEST: IN CASE OF INGESTION, WASH MOUTH OUT
W/WATER AND C ONSULT LOCAL POISON CENTER AND A MD.

Extinguishing Media:DRY CHEMICAL POWDER, CARBON DIOXIDE, WATER SPRAY,
ALCOHOL OR POLYMER FOAM.
Fire Fighting Procedures:USE NIOSH APPROVED SCBA AND FULL PROTECTIVE
EQUIPMENT TO PREVENT CONTACT WITH SKIN AND EYES.
Unusual Fire/Explosion Hazard:UPON THERMAL DECOMPOSITION, IT MAY EMIT
TOXIC GASES.

Spill Release Procedures:EVACUATE AREA. WEAR A NIOSH APPROVED
RESPIRATOR, CHEMICAL SAFETY GOGGLES, RUBBER BOOTS AND HEAVY RUBBER
GLOVES. SWEEP UP AND PLACE IN A SUITABLE CONTAINER. AVOID RAISING
DUST. HOLD FOR APPROPRIATE DIS POSAL. WASH SPILL SITE AND VENTILATE
AREA AFTER MATERIAL PICKUP IS COMPLETE.

Handling and Storage Precautions:STORE IN A TIGHTLY CLOSED CONTAINER IN
A +4C REFRIGERATOR. MATERIAL IS AN IRRITANT. AVOID CONTACT WITH
MATERIAL. AVOID PROLONGED OR REPEATED EXPOSURE. LAB SHOULD BE
EQUIPPED WITH A SAFETY SHOWER AND A N EYE WASH STATION. WASH
THOROUGHLY AFTER HANDLING MATERIAL.

Respiratory Protection:USE A NIOSH APPROVED RESPIRATOR.
Ventilation:HANDLE IN A CHEMICAL FUME HOOD WITH ADEQUATE VENTILATION.
Protective Gloves:CHEMICAL RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:ANSI APPROVED EYE WASH AND DELUGE SHOWER .
WEAR SUITABLE PROTECTIVE CLOTHING.
Supplemental Safety and Health
PHYSICAL DATA: SOLUBILITY: SOLUBLE IN DMF, ETHANOL AND WATER.
GLUTATHIONE, OXIDIZED - MOLECULAR WEIGHT: 612.6; MOLECULAR FORMULA:
C*20H*32N*6O*12S*12.

Melt/Freeze Pt:=178.C, 352.4F
Solubility in Water:SOLUBLE
Appearance and Odor:WHITE SOLID.

Stability Indicator/Materials to Avoid:YES
AVOID CONTACT WITH STRONG OXIDIZING AGENTS.
Stability Condition to Avoid:STABLE UNDER NORMAL HANDLING PROCEDURES.
Hazardous Decomposition Products:UPON THERMAL DECOMPOSITION, MAY EMIT
TOXIC GASES INCLUDING CARBON MONOXIDE, CARBON DIOXIDE, NITROGEN
OXIDES AND SULFUR OXIDES.

Waste Disposal Methods:COUNTRY, FEDERAL, STATE AND LOCAL REGULATIONS
ARE VARIED AND CHANGE FREQUENTLY. FOR THIS REASON, WE RECOMMEND
THAT YOU CONTACT YOUR LOCAL DEPARTMENT OF HEALTH SERVICES FOR
INFORMATION ON THE DISPOSAL OF THIS PRODUCT OR ARRANGE FOR
DISPOSAL BY A LICENSED DISPOSAL COMPANY.

Toxicological Information:RTECS NUMBER: MC0556500. TOXICITY DATA AND
REFERENCES: ORL; RAT; LD50: >5 G/KG 1989. KISO TO RINSHO. CLINICAL
REPORT. 23, 6793. ORL; MUS; LD50: >5 G/KG 1989. KISO TO RINSHO.
CLINICAL REPORT. 23, 6793. IVN; RAT LD50: >2 G/KG 1989. KISO TO
RINSHO. CLINICAL REPORT. 23, 6793. IVN; MUS; LD50: >2 G/KG 1989.
KISO TO RINSHO. CLINICAL REPORT. 23, 6793. SCU; RAT; LD50: >2 G/KG
1989. KISO TO RINSHO. CLINICAL REPORT. 23, 6793. SCU; MUS; LD50:
>2 G/KG 1989. KISO TO RINSHO. CLINICAL REPORT. 23, 6793. REFER TO
REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES (RTECS) FOR A
DEFINITION OF ABBREVIATIONS (ECOLOG ICAL INFO)

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:NO INFORMATION AVAILABLE. --TOXICOLOGICAL INFO: USED IN THE
ABOVE TEXT AND FOR ADDITIONAL INFORMATION. THIS REPORT CONTAINS
ONLY SELECTED INFORMATION FROM THE RTECS.

Transport Information:UN NUMBER: N/A. PROPER SHIPPING NAME: N/A. IATA
CLASS: N/A. IATA PACKING GROUP: N/A.

Federal Regulatory Information:REGULATORY INFORMATION: XI - RISK
PHRASES: R36/37/38: IRRITATING TO EYES, RESPIRATORY SYSTEM AND
SKIN. SAFETY PHRASES: S22: DO NOT BREATHE DUST. S24/25: AVOID
CONTACT WITH SKIN AND EYES. S26: IN CASE OF CONTACT WITH EYES,
RINSE IMMEDIATELY WITH PLENTY OF WATER AND SEEK MEDICAL ADVICE.
S36/37/39: WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE
PROTECTION. S45: IN CASE OF ACCIDENT OR IF YOU F EEL UNWELL, SEEK
MEDICAL ADVICE IMMEDIATELY.